|Citrocid Magnesium Plus |
Each packet 5 g contains:
Magnesium 12.648 m equivalent ;
Citric acid 2.716 g
Standard pyridoxine hydrochloride 50 mg
Citrocid magnesium plus is composed of magnesium and citrate ions both in
active form , as well as standard pyridoxine hydrochloride (Vitamin B6),
in a well balanced dosage. It is formulated in a stabilized effervescent mixture ,
in the form of sized granules ,with palatable, acidulus sweet taste.
Citrocid magnesium plus is mainly indicated to inhibit calcium oxalate stones
crystal aggregation, which is due to excessive dietetic oxalate ( exogenous) or as
a result of end products of metabolism (endogenous) .
Magnesium ions inhibit crystal growth of calcium oxalate by precipitating
exogenous dietetic oxalates, and so it inhibits its absorption through G.I.T .
Citrate ions, inhibit formation of calcium containing crystals by chelating it .
Pyridoxine hydrochloride plays an important part in the prevention of
genetic or primary hyperoxaluria which is characterized biochemically by
continued excretion of oxalic acid in urine and clinically by calcium oxalate
nephrolithiasis and nephrocalcinosis .
Generally , we can say, vitamin B6 inhibits the formation of metabolic
Indications & usage :
For prevention of hyperoxaluria and as a mild laxative.
This drug is contraindicated in some cases of impaired renal functions.
Side effects :
Hypermagnesaemia is uncommon except in the presence of renal impairment .
Sensory neuropathy may be observed in individuals consuming more than
200 mg of pyridoxine daily for very long periods.
Citrocid magnesium plus may cause G.I irritation , and watery diarrhoea .
Drug interactions :
Citrocid magnesium plus decreases the absorption of tetracycline and
biphosphonates , and administration should be separated by a number of hours.
Intestinal absorption of Aluminium hydroxide may be enhanced by citrate .
Pyridoxine reduces the therapeutic effect of levodopa.
Warnings & precautions:
Citrocid magnesium plus should be used cautiously in patients with renal impairment.
Citrocid magnesium plus decreases the incidence of diarrhoea, when taken with food.
As it crosses the placenta, the use should be avoided within 2 hours of the delivery.
Dosage & administration:
One packet to be dissolved in half glass of water and taken during
effervescing , two times daily or as prescribed by the physician .
Box of 12 packets each of 5 g .
Store at a temperature below 30 oc and R.H below 70 %