Entocid - H
Tablets
Antidiarrheal , anti-infective &antispasmodic Composition :
Each tablet contains :
Di-iodohydroxyquinoline 200 mg .
Streptomycin sulphate 200 mg .
Hyoscine - N – butyl bromide 10 mg .
Properties :
Entocid- H tablets constitute a reliable treatment of intestinal infections .
It contains three synergistic active ingredients :
Di-iodohydroxyquinoline :
Which is effective against the trophozites and cysts of Entameba histolytica located in the large intestine, because it is poorly absorbed from the GIT , the drug can reach high concentration in the intestinal lumen and produce its potent amoebicidal effect precisely at the site of infection. Streptomycin sulphate :
Is an aminoglycoside antibacterial agent which is not absorbed when given by mouth, thus no systemic action or toxicity is produced. However this route of administration is reserved for the local sterilization of the gut. Hyoscine -N- butyl bromide :
An anticholinergic agent , it exerts a specific antispasmodic action on the
smooth muscles of the gastrointestinal tract without any side effects . Indications & usage :
- Acute and chronic bacillary dysentery.
- Amoebiasis .
- Bacterial enteritis and colitis.
- Diarrhea accompanied with spasm . Contra-indications :
Patients with severe renal or hepatic failure or with blood disorders .
Hypersensitivity to Diiodohydroxyquinoline or iodine containing preparations. Side effects :
Hypersensitivity and skin reactions including urticaria or pruritus may occur. Drug interactions :
The effect of Hyoscine may be enhanced by the concomitant use of other antimuscarinic properties such as amanitidine , antihistaminics , phenothiazine , antipsychotic , and tricyclic antidepressants . warnings & precautions : Adequate fluid intake is necessary .
Diiodohydroxyquinoline may cause myelo-optic neuropathy in some patients, especially when used for a long period. Accordingly, the product should not be used for more than 10 consecutive days.
If the patient suffers from blurred vision or visual disturbance, he should tell the doctor who may advise him not to drive the car or operate machine that requires sharp vision.
Children may be likely to develop certain side effects especially if given at high doses for long time.
Caution is required in patients with renal or hepatic impairment or with thyroid disease.
If the patient must have thyroid function test, he should tell the doctor since
Diiodohydroxyquinoline may interfere with the determination of protein-bound iodine for up to 6 months.
Safety during pregnancy and in nursing mothers has not been established.
Its use is best avoided in patient with neurological disorders.
Dosage & administration:
1-2 tablets every four to six hours or as prescribed by the physician . Packing :
A carton box containing 2 strips of 10 tablets each. Storage :
Stored in a temperature not exceeding 30 o C.
Keep in dry place ( R.H not exceeding 70 % ) . | 
