| Lohydran Packets Powder for oral rehydration solution Composition:
Each packet (4.1 g) contains:
Sodium chloride 0.520 g.
Trisodium citrate dihydrate 0.580 g.
Potassium chloride 0.300 g.
Glucose anhydrous 2.700 g. Pharmacological action:
Lohydran powder for oral rehydration solution is well balanced formula
consisting of sugar and salts to replace body fluids and electrolytes lost as a result of diarrhea . Sodium chloride & Potassium chloride : replace electrolyte deficit
adequately and safely .
Glucose : enhance absorption of electrolytes and water from the intestine.
Potassium citrate: added to revert metabolic acidosis . Lohydran is characterised by its orange flavour taste which make it palatable and acceptable especially to children in addition to its easily usage in hospital and at home . Pharmacokinetics:
Sodium chloride & Potassium chloride: are readily absorbed from the
gastrointestinal tract excreted mainly by the kidney and some are lost in the
faeces and sweat.
Glucose : readily absorbed from the gastrointestinal tract , metabolized via
pyruvic or lactic acid to carbon dioxide and water with release of energy.
Potassium citrate: metabolized after absorption to bicarbonate. Indications :
Treatment of dehydration caused by gastroenteritis or diarrhea .
Excessive looses of electrolytes in the feces e.g. chronic diarrhea
associated with intestinal malabsorption or laxative abuse. Contra- indication :
Gastrointestinal tract obstruction. Side effects:
Vomiting can occur after taking oral rehydration solution, this may indicate that it was given too quickly. If vomiting occur, administration should be halted for 10 minutes then resumed in smaller, more frequent amounts. Drug Interactions: Not known .
Warnings & precautions:
* Caution is required in the following cases:
- kidney disease (including people who are producing very small amounts
or no urine).
- Liver disease.
- People on low sodium or potassium diet .
- Diabetes.
- Severe and persistent diarrhea and vomiting.
* For infants only breast-feeding or formula feed should be continued during
the hours of rehydration therapy.
* Pregnancy and lactation : Lohydran can be used safely during
Pregnancy and lactation .
Dosage & administration:
* Dissolve the contents of the packet in 200 ml fresh water (previously boiled
and cooled water for infants) and given slowly by using a spoon.
* Don' t boil the prepared solution
* The solution should be made up immediately before use and used within
one hour. If refrigerated the solution should be used within 24 hours only.
Usual dose: 200-400 ml solution after every loose stool.
Infants : 1-1½ times usual feed volume.
Child: 200 ml solution after every loose stool.
N.B: once rehydration is complete ,the patient should drink normal volume of fluids , in infant breast feeding or formula feed should be offered between oral rehydration drink . Packing :
Box of 10 packets . Storage :
Keep away from moisture & at temp. not exceeding 30oC . | 
