Properties: Aspocid -C is available in effervescent preparation . It is rapidly absorbed from gastrointestinal tract causing less gastric irritation . The use of Aspocid-C effervescent tablet results in faster onset of action, greater peak intensity and longer analgesic effects. Acetylsalicylic acid has analgesic , anti - inflammatory and antipyretic actions . It inhibits prostaglandins biosynthesis. Ascorbic acid ( vitamin C ) is an essential co-enzyme for collagen formation, tissue repair and synthesis of lipids and proteins. It acts both as reducing agent and as antioxidant. It is necessary for many physiologic functions e.g. Resistance to infection, cellular respiration and preservation of blood vessel integrity. Indications & usage : Symptomatic relief of common cold and influenza . Contra-indications : - Breast-feeding . - Gastro–intestinal ulceration . - Hemophilia - Gout . - History of hypersensitivity to aspirin and other NSAIDs. - Bronchial asthma . Side effects: Generally mild and infrequent including: GIT irritation (can be reduced by taking drug after food ). Skin and bronchospastic reactions in patients who have hypersensitivity to NSAIDs. Increased bleeding time. Drug interactions: Anticoagulants or other Antiplatelet drugs: increased risk of bleeding. Corticosteroids: increased risk of gastrointestinal bleeding and ulceration. Spironolactone: reduced diuretic effect. Acetazolamide: reduced excretion of acetazolamide (increased risk of toxicity). Acidification of urine of vitamin C may cause precipitation of urate or oxalate stones. |