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Main » Photo album » Pharmaceuticals photos » Bellacid

Composition :
Each tablet contains:
Dry Extract of Belladonna 0.01 gm.
Phenobarbitone 0.02 gm.

Properties :
Bellacid is an antispasmodic and sedative compound that contains two
synergically active substances, belladonna and pheno­barbitone.
Belladonna is a cholinergic depressant, it therefore inhibits excessive
motility of the viscera such as the stomach, intestines, colon, ureters, urinary
bladder and biliary passages. It also diminishes excessive gastric and other
secretions. Phenobarbitone is a central sedative, an action which is required
in such cases where spasm is coupled with anxiety. Moreover, the
barbiturates enhance the anticholinergic action of belladonna.

Indications and usage :
- Peptic ulcer - Hyperacidity
- intestinal colic - Spastic colon
- Pylorospasm - Dysmenorrhea
- Nocturnal enuresis in children.

Prostatic enlargement .
Paralytic ileus , pyloric stenosis , and ulcerative colitis .
Myasthenia gravis .
Narrow or angle closure glaucoma .
Ischaemic heart failure , and myocardial infarction .
Severe respiratory depression .

Side effects :
- Adverse effects are dose related and are usually reversible when therapy is
discontinued and includes ; dry mouth with difficulty of swallowing , reduced
bronchial secretion , dilatation of eye pupil ( mydriasis ) with loss of
accommodation (cycloplegia ), transient bradycardia , followed by
tachycardia , and constipation .
Hypersensitive reaction is not common and may occurs as conjunctivitis
or skin rash .

Drug interactions :
The effect of belladonna may be enhanced by the concomitant use with other drugs having ;
. anti-muscarinic properties as amantadine .
. anti-histaminics .
. phenothiazine antipsychotic and tricyclic antidepressants .
MAOIs may enhance the anti-muscarinic effect .
Antimuscarinics and parasympathomimetics may counteract each others effects .
Valproate and phenytoin rise phenobarbitone concentration in plasma .

Warnings & precautions :
Children and elderly as the drug may cause confusion to them .
In patients with conditions characterized by tachycardia , such as
thyrotoxicosis and heart failure where they may further accelerate heart rate.
In the treatment of parkinsonism the dose should be increased gradually and
should not be withdrawn abruptly .

Dosage & administration:
1 to 4 tablets daily .
For nocturnal enuresis: 1/2 to 1 tablet, 1 hour before bedtime.

Box of 30 tablets(strips of 10 tablets each ) .

Storage :
Store at a temperature below 30 oc and R.H below 70 %

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Date: 2010-04-13 | Tags: Bellacid | Added by: Modajaa
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